
机械装备与控制工程系
xiaoling@me.ustb.edu.cn
本科生课程:《自然界中的相变》双语课、《生物力学工程》双语课、《生物机械工程》双语课
研究生课程:《生物工程》双语课
教育经历:
1996.09-2000.07 北京理工大学应用力学系,学士
2000.09-2003.01 北京理工大学应用力学系,硕士
2003.01-2006.12 香港科技大学机械工程系,博士
工作经历:
2007.01-2007.12 香港大学医学院 博士后
2008.01-2012.07 ok138cn太阳集团 讲师
2012.07-2017.07 ok138cn太阳集团 副教授
2017.07-现在 ok138cn太阳集团 教授
2018.07-现在 ok138cn太阳集团 博士生导师
2013.02-2013.08 美国西北大学 访问学者
2013.09-2014.02 美国哈佛大学 访问学者
成果与荣誉:
指导研究生王同学于2013年荣获国家奖学金(奖学金数额:2万元)。
指导研究生侯同学于2014年荣获国家奖学金(奖学金数额:2万元)。
指导研究生孟同学于2015年荣获国家奖学金(奖学金数额:2万元)。
指导研究生赵同学于2016年荣获国家奖学金(奖学金数额:2万元)。
指导研究生唐同学于2024年荣获国家奖学金(奖学金数额:2万元)。
指导研究生张同学于2024年荣获国家奖学金(奖学金数额:2万元)。
指导研究生王同学于2023年荣获“厦钨-厦门金鹭”奖学金(金额:8千元)。
指导研究生孟同学于2015年获得北京市优秀毕业生荣誉称号。
指导研究生张同学于2024年获得北京市优秀毕业生荣誉称号。
指导研究生多人次荣获校优秀三好学生、校优秀毕业生、优秀学生干部、十佳学术之星等多项奖励和荣誉称号。
指导本科生曾同学参加SRTP项目获得校二等奖。
指导本科生曾同学毕业设计获得第七届“精雕杯”毕业设计大赛北方赛区三等奖。
2019年荣获ok138cn太阳集团第六届“研师亦友--我最喜爱的导师”荣誉称号。
先后主持国家自然科学基金委资助的青年项目、青年面上连续项目,面上项目,重点国际合作与交流项目子项目6项。
主持北京市、高校和其他科研项目。
多篇发表成果被选为期刊封面文章。
多篇成果发表在Physics of Life Review、Colloids and Surfaces B: Biointerfaces、Journal of Basic Microbiology等国内外交叉学科期刊。
近五年发表SCI论文近百篇
获国家发明专利2项。
参与编著教材3部。
获得北京市高校青年英才计划奖励。
2020年被中国力学学会推荐为中国青年女科学家奖候选人。
多次参加并参与组织国内外和北京市生物力学、微生物学相关学术会议,并作邀请报告。
多次担任本科班班主任
指导硕士和博士研究生近40名,本科生近80名
毕业研究生就业在高校、研究所以及其他国企和国际国内知名企业,如:
1.ok138cn太阳集团,
2.郑州大学,
3.首都机场集团有限公司北京大兴国际机场,
4.机械工业和信息研究院,
5.北方华创科技集团股份有限公司,
6.中国电信股份有限公司,
7.博世中国投资有限公司,
8.小米通讯技术有限公司,
9.航天科工集团第四研究院,
10.中电41所,
11.北京市第八中学,
12.北京强度环境研究所,
13.山东新华医疗器械股份有限公司,
14.北京华航无线电测量研究所,
15.山东泰开高压开关有限公司
16.长沙矿山研究院有限责任公司
17.湘潭钢铁集团有限公司
18.中芯北方集成电路制造(北京)有限公司
19.中国人民解放军32381部队
20.度小满金融
21.浙江省自然科学基金委员会办公室
22.华为技术有限公司
和哈佛大学教授David Wetiz院士合作多篇文章,发表在国际顶级期刊。首次设计并实现对同一菌种多重荧光标记,开发出在不破坏细菌生物膜完整性情况下,同时在时间和空间多尺度观测细菌生物膜的生长、基因表达细胞的演化和分布的荧光显微镜技术和实验观测平台,实验方法获得国家发明专利。
和香港大学孙庆平教授合作文章,首次提出生物系统力学相变问题并进行研究进展综述,发表在国内顶级期刊。
和英国剑桥大学Rafi教授合作综述文章,首次对细菌相变领域的研究进展进行了综述,发表在国际顶级期刊。
多次应邀在哈佛大学David Wetiz 院士讨论班做报告,讨论交流。
多次受邀参加国际会议并作学术报告,比如
a)美国波士顿(NSF summer workshop on “Materiomics: Merging Biology and Engineering in Multiscale Structures and Materials”),
b)英国爱丁堡(Topical Research Meeting on Physical Principles of Biological and Active Systems),
c)西班牙马德里(The 4th World Congress and Expo on Applied Microbiology),
d)瑞士Les Diablerets(Gordon Research Conference “Biointerface Science”),
e)爱尔兰都柏林大学(Biofilm 2017- 10th International Conference on Biofilm Reactors),
f)加拿大(The University of Western Ontario),邀请报告,
g)美国亚特兰大佐治亚理工大学(A Symposium on Soft Matter Forefronts),
h)丹麦Aarhus University(Biofilms 8 Conference),
i)意大利(Gordon Research Conference- Biointerface Science: Surfaces and Compartments in Biology and Medicine, Renaissance Tuscany Il Ciocco Lucca (Barga)),
j)澳大利亚 Perth, Western Australia (The 5 International Symposium on Functional Materials),
k)韩国首尔(Pacific Graphics 2019),
l)中国 香港 (IUTAM Symposium in Hong Kong on "Hysteresis and pattern evolution in non-equilibrium solid-solid phase transitions),
m)中国 北京 清华大学(Symposium on Frontiers of Cell and Tissue Evolution Dynamics, Beijing Convention Center),
等国际国内会议上作学术报告。
代表性论著:
1.Xianyong Li, Rui Kong, Jiankun Wang, Jin Wu, Ketai He, Xiaoling Wang. The formation mechanism of Bacillus subtilis biofilm surface morphology under competitive environment. March 2023 Canadian Journal of Microbiology. DOI: 10.1139/cjm-2023-0014
2.Xianyong Li, Rui Kong, Jiankun Wang, Jin Wu, Xiaoling Wang. Matrix Producing Cells Induce the Morphological Difference in the Bacillus subtilis Biofilm. March 2023 Indian Journal of Microbiology. DOI: 10.1007/s12088-023-01073-w
3.Xiaoling Wang, Raphael Blumenfeld, Xiqiao Feng, David A. Weitz. ‘Phase transitions’ in bacteria – From structural transitions in free living bacteria to phenotypic transitions in bacteria within biofilms. Physics of Life Reviews. 2022, 43, 98-138. https://doi.org/10.1016/j.plrev.2022.09.004
4.Fulin Dong, Song Liu, Duohuai Zhang, Jinchang Zhang, Xiaoling Wang. Matrix-producing cells formed ‘Van Gogh bundles’ facilitate Bacillus subtilis biofilm self-healing. Environmental Microbiology Reports. 17 May 2022. DOI: 10.1111/1758-2229.13099
5.Jiankun Wang, Xianyong Li, Rui Kong, Jin Wu, Xiaoling Wang. Fractal morphology facilitates Bacillus subtilis biofilm growth. Environmental Science and Pollution Research. 15 March 2022. DOI: 10.1007/s11356-022-19817-4
6.JinChang Zhang, Song Liu, Fulin Dong, Duohuai Zhang, Xiaoling Wang. Biofilm streamer growth dynamics in various microfluidic channels. Canadian Journal of Microbiology. 22 January 2022. DOI: 10.1139/cjm-2021-0346
7.Song Liu, Fulin Dong, Duohuai Zhang, Jinchang Zhang, Xiaoling Wang. Effect of microfluidic channel geometry on Bacillus subtilis biofilm formation. Biomedical Microdevices. 18 January 2022. 24 (1), 1-11. DOI: 10.1007/s10544-022-00612-4
8.Fulin Dong, Song Liu, Duohuai Zhang, Jinchang Zhang, Xiaoling Wang, Hui Zhao. Osmotic Pressure Induced by Extracellular Matrix Drives Bacillus Subtilis Biofilms’ Self-healing. Computational Biology and Chemistry. 15 January 2022. 97:107632. DOI: 10.1016/j.compbiolchem.2022.107632
9.Xiaoling Wang, Fulin Dong, Jiali Liu, Yifan Tan, Shuaishuai Hu, Hui Zhao. The self‑healing of Bacillus subtilis bioflms. Archives of Microbiology. 31 August 2021. https://doi.org/10.1007/s00203-021-02542
10.Shuaishuai Hu, Xiaoling Wang, Yifan Tan, Jiali Liu, Hui Zhao. ‘Chain and running’ induced by mechanical interactions among cells of different phenotypes in the Bacillus subtilis biofilm. European Biophysics Journal. 2021, 50: 1013–1023. https://doi.org/10.1007/s00249-021-01562-0
11.Xiaoling Wang, Duohuai Zhang, Fulin Dong, Song Liu, Jinchang Zhang, Hui Zhao. Cell differentiation and motion determine the Bacillus subtilis biofilm morphological evolution under the competitive growth. Journal of Basic Microbiology 2021, 61(5), 396-405.
12.Xiaoling Wang, Yifan Tan, JiaLi Liu, Shuaishuai Hu, Hui Zhao. The Evolving Wrinkle Pattern of The Bacillus Subtilis Biofilm Providing More Living Space for Cells. Journal of Mechanics in Medicine and Biology. 2020, 20 (7), 2050048.
13.Xiaoling Wang, Yuhao Kong, Hui Zhao and Xiaoqiang Yan. Dependence of the Bacillus subtilis biofilm expansion rate on phenotypes and the morphology under different growing conditions. Development Growth and Regeneration. September 2019, 61, (7-8), 431-443. DOI: 10.1111/dgd.12627
14.Hui Zhao, Xuan Li, Wencheng Wang, Xiaoling Wang, Shaodong Wang, Na Lei, Xiangfeng Gu. Polycube Shape Space. Pacific Graphics 2019, 2019, 38 (7), 1-12.
15.Xiaoling Wang, Zhaocan Wang, Xing Shen, Yuhao Kong, Hui Zhao, Xiaoqiang Yan. Studying the internal stress heterogeneity of the growing biofilm by the micropillar deformation of the growing substrate. Journal of Mechanics in Medicine and Biology. 2019, 19(06), 1950070. DOI: 10.1142/S0219519419500702
16.Xiaoling Wang, Xing Shen, Zhaocan Wang, Yuhao Kong. Viscoelasticity variation in a biofilm-mediated Bacillus subtilis suspension induced by adding polyethylene glycol. European Biophysics Journal, 2019, 48(7), 599-608. DOI 10.1007/s00249-019-01385-0
17.Hui Zhao, Kehua Su, Chenchen Li, Boyu Zhang, Lei Yang, Na Lei, Xiaoling Wang, Steven J. Gortler, Xianfeng Gu. Mesh Parameterization Driven by Unit Normal Flow. COMPUTER GRAPHICS Forum 2019. https://doi.org/10.1111/cgf.13660
18.Hui Zhao, Xuan Li, Huabin Ge, Na Lei, Min Zhang, Xiaoling Wang, Xianfeng Gu. Conformal mesh parameterization using discrete Calabi flow. Computer Aided Geometric Design 2018, 63, 96-108. DOI: 10.1016/j.cagd.2018.03.001
19.Xiaoling Wang, Kai Zhao and Hui Zhao. Finite Element Simulation of Biofilm Viscoelastic Behavior under Various Loadings. Journal of Mechanics in Medicine and Biology. 2018, 18(5), 1850056. DOI: 10.1142/S0219519418500562
20.Siddarth Srinivasan, Ioana D. Vladescu, Stephan A. Koehler, Xiaoling Wang, Madhav Mani, and Shmuel M. Rubinstein. Matrix Production and Sporulation in Bacillus subtilis Biofilms Localize to Propagating Wave Fronts. Biophysical Journal 114, 1–9, March 27, 2018. https://doi.org/10.1016/j.bpj.2018.02.002
21.Cheng Zhang, Bo Li, Jing-Ying Tang, Xiaoling Wang, Zhao Qin and Xi-Qiao Feng. Experimental and theoretical studies on the morphogenesis of bacterial biofilms. Soft Matter. September 2017, 13, 7389-7397. DOI:10.1039/C7SM01593C
22.Xiaoling Wang, Shuo Meng and Jingshi Han. A Continuum Theoretical Model and Finite Elements Simulation of Bacterial Flagellar Filament Phase Transition. Journal of Biomechanics. October 2017, 63 (3), 21-31. DOI: http://dx.doi.org/10.1016/j.jbiomech.2017.09.012
23.Xiaoling Wang, Shuo Meng and Jingshi Han. Morphologies and phenotypes in Bacillus subtilis biofilms. Journal of Microbiology. August 2017, 55 (8), 619-627. DOI 10.1007/s12275-017-7041-z
24.Xianlong Zhang, Xiaoling Wang, Qingping Sun. Modeling of Biofilm Growth on Ager Substrate Using the Extended Finite Element Method. Procedia IUTAM. 2017 (23), 33-41. doi: 10.1016/j.piutam.2017.06.003
25.Xianlong Zhang, Xiaoling Wang, Kai Nie, Mingpeng Li, Qingping Sun. Simulation of Bacillus subtilis biofilm growth on agar plate by diffusion–reaction-based continuum model. Physical Biology. July 2016, 13 (4): 046002. DOI: 10.1088/1478-3975/13/4/046002
26.Jun-ichi Matsushita, Tatsuki Satsukawa, Naoya Iwamoto, Xiaoling Wang, Jianfeng Yang, Tomoyo Goto, Tohru Sekino, Xiaoyong Wu, Shu Yin, and Tsugio Sato. Oxidation of Pentatitanium Trisilicide (Ti5Si3) Powder at High Temperature. Materials Science Forum. 2016, 868, 38-42. DOI: 10.4028/www.scientific.net/MSF.868.38
27.Xiaoling Wang, Mudong Hao, Xin Du, Guoqing Wang, Junichi Matsushita. The mechanical analysis of the biofilm streamer nucleation and geometry characterization in microfluidic channels. Computational and Mathematical Methods in Medicine. 2016: 1-10. http://dx.doi.org/10.1155/2016/7819403.
28.Xiaoling Wang, Stephan A. Koehler, James N. Wilking,Naveen N. Sinha, Matthew T. Cabeen, Siddarth Srinivasan, Agnese Seminara, Shmuel Rubinstein, Qingping Sun, Michael P. Brenner, David A. Weitz. Probing Phenotypic growth in expanding Bacillus subtilis biofilms, Applied Microbiology and Biotechnology, 2016, 100(10), 4607-4615. DOI: 10.1007/s00253-016-7461-4.
29.Xiaoling Wang, Jingshi Han, Kui Li, Guoqing Wang and Mudong Hao, Multi-Layer composite mechanical modeling for the inhomogeneous biofilm mechanical behavior. Computational Biology and Chemistry. 2016, 14(4), 1650014-(1-14). DOI: http://dx.doi.org/10.1142/S0219720016500141
30.Jun-ichi Matsushita, Tomoyuki Tsuchiyama, Kazuya Hamaguchi, Naoya Iwamoto, Xiaoling Wang, Jianfeng Yang, Tohru Sekino, Xiaoyong Wu, Shu Yin, and Tsugio Sato. Anatase Type Titanium Dioxide Prepared by Oxidation of Titanium Carbide. Materials Science Forum, 2016, Vol. 860, 92-96. DOI: 10.4028/www.scientific.net/MSF.860.92
31.Xiaoling Wang, Mudong Hao and Guoqing Wang, Numerical simulation of wrinkle morphology formation and the evolution of different Bacillus subtilis biofilms. Water Science and Technology. 2016, 73(3), 527-534. DOI: 10.2166/wst.2015.486
32.Xiaoling Wang, Yingrui Hou, Guoqing Wang, Mudong Hao and Hao Li. Parametric Optimization of Metal Conductors in Flexible Electronics Design. Circuit World. 2016, Vol.42 (2), 89-94. DOI:10.1108/CW-08-2015-0043
33.Liang Dong, Runhua Zhou, Xiaoling Wang, Gengkai Hu, Qingping Sun. On interfacial energy of macroscopic domains in polycrystalline NiTi shape memory alloys. International Journal of Solids and Structures. 2016, 80, 445-455.
34.Xiaoling Wang, Guoqing Wang and Mudong Hao. Modeling of the Bacillus subtilis Bacterial Biofilm Growing on an Agar Substrate, Computational and Mathematical Methods in Medicine. 2015, 9, 1-10. DOI:10.1155/2015/581829
35.Xiaoling Wang, Hao Li and Guoqing Wang. Effect of the geometric parameters of elastomer substrates on the flexibility of stretchable electronics, Chinese Journal of Engineering, 2015, 37 (s1), 24-28
36.Xiaoling Wang, and Qingping. Sun. Modeling of rate-dependent phase transition in bacterial flagellar filament. Materials Research Bulletin, Materials Research Bulletin, 2013, 43, 5019-5025. DOI: 10.1016/j.materresbull.2013.05.009.
37.Xiaoling Wang, QingPing Sun. Mechanical modeling of the bistable bacterial flagellar filament. Acta Mech Solida Sinica, 2011. 24(S), 1-16.
38.Xiaoling Wang, Yongjun He, QingPing Sun. Simulation of Bacterial flagellar phase transition by non-convex and non-local continuum modeling. Theoretical & Applied Mechanics Letters. 2011, 1 (4): 044001-6.
39.Xiaoling Wang, QingPing Sun. Mechanical Analysis of Phase Transition Experiments of the Bacterial Flagellar Filament. Acta mechanica Sinica, 2010, 26 (5), 777-785.
40.Xiaoling Wang, QingPing Sun. The review of phase transition in biological systems. Advances in Mechanics, 2010 ,40 (1): 64-80 (in Chinese).
41.Xiaoling Wang, GengKai Hu. Stress transfer for a SMA fiber pulled out from an elastic matrix and related bridging effect. Composites part A - Applied Science and Manufacturing, 2005, 36 (8): 1142-1151.
42.Xiaoling Wang, Hui Zhao, Virtual Medical Model Modification with Laplacian System, International Conference on Biomedical Engineering & Informatics, 2010, 3(1), 1296-1299.
43.Xiaoling Wang, Qiang Zhang, The Mechanical Property Analysis of Circular Saw Blades under Different Rotational Speeds, Advanced Materials Research, 2010, 145, 365-370.
44.Xiaoling Wang, Yong Zhang, The Analysis on Different Circular Saw Structures for Reducing Saw Noise, Advanced Materials Research. 2010, 145, 551-556.
45.Xiaoling Wang, Hui Zhao, Surface Based Virtual Mechanical Equipment Modification, Advanced Materials Research, 2010, 149, 693-697.
46.Xiaoling Wang, Hui Zhao, Virtual Mechanical Equipment Model Smoothing, Advanced Materials Research, 2010, 156, 355-359.
47.Xiaoling Wang, Zhongjun Yin and Yanlin Li, The stress analysis of different circular saw structures during cutting, Advanced Materials Research. 2011, 228, 471-476.
48.Xiaoling Wang, Zhongjun Yin and Chao Zhang, The analysis of dynamic characteristics in reduction of the circular saw idling noise, Advanced Materials Research, 2011, 229, 477-483.
49.Xiaoling Wang, Zhongjun Yin and Chao Zhang, The mechanical analysis of the composite reinforced circular saw blade, Advanced Materials Research, 2011, 228: 484-489.
专利:
1.王晓玲*; 戴维A·韦茨; 一种实时观测枯草芽孢杆菌生物膜生长过程中不同基因表现型细胞和分布的方法, 2018-2-24, 中国, 201510388619.9.
2.王晓玲*; 戴维A·韦茨; 一种采用液滴微流控技术提高微生物燃料电池的输出功率的实验方法, 2017-05-27, 中国, 201510388861.6.
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